Vhh Protein. A recombinant VHH domain designated nanobody (Nb) is highly soluble and does not show any tendency to associate with other hydrophobic protein surfaces Conventional antibodies are composed of two heavy and two light chains The targetbinding module is composed of two noncovalently associated variable domains VH and VL In intact antibodies the proper orientation.
Single Domain Antibodies For The Knockdown Of Cytosolic And Nuclear Proteins Boldicke 2017 Protein Science Wiley Online Library from onlinelibrary.wiley.com
GFP VHH recombinant binding protein iST GFPTrap Kit for IP and MS sample preparation Synonyms antiGFP V H H GFP V H H GFPBindingProtein GFP Nanobody or antiGFP single domain antibody (sdAb) Benefit from GFPTrap for Immunoprecipitation (IP) Effective pulldown of GFPfusion proteins for consistent results No heavy & light antibody chains short.
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Reference BurgessBrown NA Sharma S Sobott F Loenarz C Oppermann U Gileadi O Codon optimization can improve expression of human genes in Escherichia coli A multigene studyProtein Expr Purif May 2008 59(1) 94102 Significant Increase Drug Target Proteins Expression Level in Ecoli Figures below manifested the effectiveness of the OptimumGene.
Single Domain Antibodies For The Knockdown Of Cytosolic And Nuclear Proteins Boldicke 2017 Protein Science Wiley Online Library
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